Abstrakt
Cel: Ocena wyników leczenia par z niepłodnością lub poronieniem z podejśćia naprawczej medycyny rozrodu, oraz identyfikacja czynników predykcyjnych sukcesu.
Metody: Było to badanie retrospektywne 282 par malżeńskich , które zostały objęte programem w 2 przychodniach ginekologicznych w okresie od maja 2010 r. do grudnia 2014 r. Pary obserwowano do końca ciąży lub wycofania się z programu. Wszystkie pary nauczono obserwacji cyklu za pomocą Creighton Model FertilityCare System lub metody objawowo-termicznej i prawie wszystkie otrzymały dodatkowe leczenie. Głównym wynikiem były porody żywym dzieckiem, wtórne wyniki obejmowały poczęcie, nieudane ciąże, niską masę urodzeniową i wcześniactwo. Wyniki: W analizie life table skorygowany skumulowany odsetek pierwszych poczęć dla par na 24 miesięcy leczenia wynosił 77,7% (wskaźnik surowy 47,9%). Skorygowany skumulowany odsetek urodzeń żywych (obejmował tylko kobiety, których pierwsza ciąża w programie zakończyła się sukcesem) wyniósł 73,6% (117 porodów, wskaźnik surowy 41,5%). Surowy odsetek pierwszych żywych urodzeń (124 urodzeń, w tym 7 żywych urodzeń u kobiet, których pierwsza ciąża skoczyla sie poronieniem) wyniósł 44%. Średni czas do zajścia w ciążę wynosił 8 miesięcy (od 1 do 44 miesięcy). Wszystkie porody oprócz jednego były pojedynczymi. Były tylko 3 porody przedwczesne (do 36 tygodni), z jednym z nich we wspomnianej ciąży bliźniaczej. Tylko dzieci z tych 3 ciąż urodziły się z wagą mniejszą niż 2500 g. Sprzyjające predyktory żywych urodzeń były młodszy wiek, krótszy czas starań o ciążę, rzetelność w wykonaniu zaleceń lekarza, ciąża w wywiadzie. Niekorzystne: hiperprolaktynemia, mięśniaki macicy, endometrioza, czynnik męski.
Wniosek: Wyniki leczenia par z niepłodnością lub nawracającym poronieniem wedlug zasad naprawczej medycyny rozrodu w Ukrainie były porównywalne z wynikami takiego leczenia w Irlandii i Kanadzie.
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