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Abstract
Congenital or acquired disorders of hypophysys may led to impaired fertility in men. The most common is hypogonadotropic hypogonadism (HH). Congenital HH is caused by reduction of synthesis, secretion or action of gonadoliberin GnRH), and is characterized by an absence of puberty and infertility, while acquired HH is associated mainly with impaired fertility. In young men with congenital HH after stimulation of puberty and in patients with acquired HH, hormonal stimulation of spermatogenesis is necessary. In patients with HH and impaired fertility gonadotropin therapy effectively stimulates or improves spermatogenesis, and may help the patient obtain offspring using the natural method or with the use of assisted reproduction techniques, while gonadotropins are not recommended for men with idiopathic infertility and normal luteinizing hormone (LH), and follicle-stimulating hormone (FSH) levels.
Key words: infertility, hypogonadotropic hypogonadism, spermatogenesis